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Lactate causes downregulation of Helicobacter pylori adhesin genes sabA and labA while dampening the production of proinflammatory cytokines
Chronic inflammation induced by Helicobacter pylori is strongly associated with gastric cancer development, which is influenced by both bacterial virulence and host genetics. The sialic acid-binding adhesin SabA and the MUC5AC-binding adhesin LabA are important H. pylori virulence factors that facil...
Autores principales: | Somiah, Tanvi, Gebremariam, Hanna G., Zuo, Fanglei, Smirnova, Ksenija, Jonsson, Ann-Beth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681763/ https://www.ncbi.nlm.nih.gov/pubmed/36414643 http://dx.doi.org/10.1038/s41598-022-24311-5 |
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