Efferocytosis drives myeloid NLRP3 dependent inflammasome signaling secretion of IL-1β to promote tumor growth

Caspase-1 signaling in myeloid suppressor cells can promote T-cell independent cancer progression, but the regulation of inflammasome signaling within the highly heterogeneous myeloid population in the tumor milieu remains elusive. To resolve this complexity, single cell transcriptomic profile of He...

Descripción completa

Detalles Bibliográficos
Autores principales: Lang, Cara, Roy, Sohini, Wang, Yu, Graves, Diana, Xu, Yaomin, Serezani, C. Henrique, Korrer, Michael, Kim, Young J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681818/
https://www.ncbi.nlm.nih.gov/pubmed/36439171
http://dx.doi.org/10.3389/fimmu.2022.993771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681818/
https://www.ncbi.nlm.nih.gov/pubmed/36439171
http://dx.doi.org/10.3389/fimmu.2022.993771

Ejemplares similares