Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB

The nuclear receptor REV-ERB plays an important role in a range of physiological processes. REV-ERB behaves as a ligand-dependent transcriptional repressor and heme has been identified as a physiological agonist. Our current understanding of how ligands bind to and regulate transcriptional repressio...

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Detalles Bibliográficos
Autores principales: Murray, Meghan H., Valfort, Aurore Cecile, Koelblen, Thomas, Ronin, Céline, Ciesielski, Fabrice, Chatterjee, Arindam, Veerakanellore, Giri Babu, Elgendy, Bahaa, Walker, John K., Hegazy, Lamees, Burris, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681850/
https://www.ncbi.nlm.nih.gov/pubmed/36414641
http://dx.doi.org/10.1038/s41467-022-34892-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681850/
https://www.ncbi.nlm.nih.gov/pubmed/36414641
http://dx.doi.org/10.1038/s41467-022-34892-4

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