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Genome wide DNA methylation analysis identifies novel molecular subgroups and predicts survival in neuroblastoma

BACKGROUND: Neuroblastoma is the most common malignancy in infancy, accounting for 15% of childhood cancer deaths. Outcome for the high-risk disease remains poor. DNA-methylation patterns are significantly altered in all cancer types and can be utilised for disease stratification. METHODS: Genome-wi...

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Detalles Bibliográficos
Autores principales: Lalchungnunga, H., Hao, Wen, Maris, John M., Asgharzadeh, Shahab, Henrich, Kai-Oliver, Westermann, Frank, Tweddle, Deborah A., Schwalbe, Edward C., Strathdee, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681858/
https://www.ncbi.nlm.nih.gov/pubmed/36175618
http://dx.doi.org/10.1038/s41416-022-01988-z