A CRISPR endonuclease gene drive reveals distinct mechanisms of inheritance bias

CRISPR/Cas gene drives can bias transgene inheritance through different mechanisms. Homing drives are designed to replace a wild-type allele with a copy of a drive element on the homologous chromosome. In Aedes aegypti, the sex-determining locus is closely linked to the white gene, which was previou...

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Detalles Bibliográficos
Autores principales: Verkuijl, Sebald A. N., Gonzalez, Estela, Li, Ming, Ang, Joshua X. D., Kandul, Nikolay P., Anderson, Michelle A. E., Akbari, Omar S., Bonsall, Michael B., Alphey, Luke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681865/
https://www.ncbi.nlm.nih.gov/pubmed/36414618
http://dx.doi.org/10.1038/s41467-022-34739-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681865/
https://www.ncbi.nlm.nih.gov/pubmed/36414618
http://dx.doi.org/10.1038/s41467-022-34739-y

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