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ZC3H11A loss of function enhances NF-κB signaling through defective IκBα protein expression

ZC3H11A is a cellular protein associated with the transcription export (TREX) complex that is induced during heat-shock. Several nuclear-replicating viruses exploit the mRNA export mechanism of ZC3H11A protein for their efficient replication. Here we show that ZC3H11A protein plays a role in regulat...

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Detalles Bibliográficos
Autores principales: Darweesh, Mahmoud, Younis, Shady, Hajikhezri, Zamaneh, Ali, Arwa, Jin, Chuan, Punga, Tanel, Gupta, Soham, Essand, Magnus, Andersson, Leif, Akusjärvi, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9681899/
https://www.ncbi.nlm.nih.gov/pubmed/36439101
http://dx.doi.org/10.3389/fimmu.2022.1002823