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Machine learning identifies characteristics molecules of cancer associated fibroblasts significantly correlated with the prognosis, immunotherapy response and immune microenvironment in lung adenocarcinoma

BACKGROUND: Lung adenocarcinoma (LUAD) is a highly lethal disease with a dramatic pro-fibrocytic response. Cancer-associated fibroblasts (CAFs) have been reported to play a key role in lung adenocarcinoma. METHODS: Marker genes of CAFs were obtained from the Cell Marker website. Single sample gene s...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Zhang, Xunlang, Du, Kangming, Wu, Xinhui, Zhou, Yexin, Chen, Diang, Zeng, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682016/
https://www.ncbi.nlm.nih.gov/pubmed/36439484
http://dx.doi.org/10.3389/fonc.2022.1059253