Cargando…

Machine learning identifies characteristics molecules of cancer associated fibroblasts significantly correlated with the prognosis, immunotherapy response and immune microenvironment in lung adenocarcinoma

BACKGROUND: Lung adenocarcinoma (LUAD) is a highly lethal disease with a dramatic pro-fibrocytic response. Cancer-associated fibroblasts (CAFs) have been reported to play a key role in lung adenocarcinoma. METHODS: Marker genes of CAFs were obtained from the Cell Marker website. Single sample gene s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Qian, Zhang, Xunlang, Du, Kangming, Wu, Xinhui, Zhou, Yexin, Chen, Diang, Zeng, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682016/ https://www.ncbi.nlm.nih.gov/pubmed/36439484 http://dx.doi.org/10.3389/fonc.2022.1059253

Ejemplares similares

Research into the biological differences and targets in lung cancer patients with diverse immunotherapy responses
por: Zhang, Xunlang, et al.
Publicado: (2022)

Effect of TTN Mutations on Immune Microenvironment and Efficacy of Immunotherapy in Lung Adenocarcinoma Patients
por: Wang, Zhe, et al.
Publicado: (2021)

Efficacy of electroacupuncture for the treatment of asthenozoospermia: A protocol for systematic review and meta-analysis
por: Wu, Xinhui, et al.
Publicado: (2021)

Integrative analysis illustrates the role of PCDH7 in lung cancer development, cisplatin resistance, and immunotherapy resistance: an underlying target
por: Li, Huakang, et al.
Publicado: (2023)

JAG1 is correlated to suppressive immune microenvironment and predicts immunotherapy resistance in lung adenocarcinoma
por: He, Jing, et al.
Publicado: (2023)

Cuproptosis-related lncRNA signatures: Predicting prognosis and evaluating the tumor immune microenvironment in lung adenocarcinoma
por: Zhang, Pengpeng, et al.
Publicado: (2023)

Cancer-associated fibroblasts refine the classifications of gastric cancer with distinct prognosis and tumor microenvironment characteristics
por: Gu, Lei, et al.
Publicado: (2023)

The immune escape signature predicts the prognosis and immunotherapy sensitivity for pancreatic ductal adenocarcinoma
por: Lu, Hao, et al.
Publicado: (2022)

Cuproptosis-related risk score predicts prognosis and characterizes the tumor microenvironment in colon adenocarcinoma
por: Wang, Jinyan, et al.
Publicado: (2023)

Translational Learnings in the Development of Chemo-Immunotherapy Combination to Bypass the Cold Tumor Microenvironment in Pancreatic Ductal Adenocarcinoma
por: Kaplon, Hélène
Publicado: (2022)

Development and validation of cancer-associated fibroblasts-related gene landscape in prognosis and immune microenvironment of bladder cancer
por: Zhang, Meng, et al.
Publicado: (2023)

Characterization and Prognosis of Biological Microenvironment in Lung Adenocarcinoma through a Disulfidptosis-Related lncRNAs Signature
por: Yang, Zhuo, et al.
Publicado: (2023)

Cuproptosis-related signature predicts prognosis, immunotherapy efficacy, and chemotherapy sensitivity in lung adenocarcinoma
por: Wu, Gujie, et al.
Publicado: (2023)

The Interferon Gamma-Related Long Noncoding RNA Signature Predicts Prognosis and Indicates Immune Microenvironment Infiltration in Colon Adenocarcinoma
por: Liu, Cong, et al.
Publicado: (2022)

Cell Trajectory-Related Genes of Lung Adenocarcinoma Predict Tumor Immune Microenvironment and Prognosis of Patients
por: Luo, Yu, et al.
Publicado: (2022)

Focus on pattern recognition receptors to identify prognosis and immune microenvironment in colon cancer
por: Ren, Pengtao, et al.
Publicado: (2022)

Comprehensive analysis of the significance of METTL7A gene in the prognosis of lung adenocarcinoma
por: Pan, Ya-Qiang, et al.
Publicado: (2022)

Comprehensive Analysis of 5-Methylcytosine (m(5)C) Regulators and the Immune Microenvironment in Pancreatic Adenocarcinoma to Aid Immunotherapy
por: Wang, Ronglin, et al.
Publicado: (2022)

Comprehensive analysis of the prognosis, tumor microenvironment, and immunotherapy response of SDHs in colon adenocarcinoma
por: Nan, Han, et al.
Publicado: (2023)

Establishment of lactate-metabolism-related signature to predict prognosis and immunotherapy response in patients with colon adenocarcinoma
por: Zou, Zhengrong, et al.
Publicado: (2022)

Reveal the Heterogeneity in the Tumor Microenvironment of Pancreatic Cancer and Analyze the Differences in Prognosis and Immunotherapy Responses of Distinct Immune Subtypes
por: Wang, Xiaoqin, et al.
Publicado: (2022)

Machine learning-based neddylation landscape indicates different prognosis and immune microenvironment in endometrial cancer
por: Li, Yi, et al.
Publicado: (2023)

Exploration the Significance of a Novel Immune-Related Gene Signature in Prognosis and Immune Microenvironment of Breast Cancer
por: Zhao, Yajie, et al.
Publicado: (2020)

The Immune Microenvironment in Mesothelioma: Mechanisms of Resistance to Immunotherapy
por: Chu, Gerard J., et al.
Publicado: (2019)

Macrophages in Osteosarcoma Immune Microenvironment: Implications for Immunotherapy
por: Luo, Zhong-Wei, et al.
Publicado: (2020)

Review of biomarkers for response to immunotherapy in HNSCC microenvironment
por: Chen, Shaoshi, et al.
Publicado: (2023)

Editorial: Tumor microenvironment, inflammation, and resistance to immunotherapies
por: Decock, Julie, et al.
Publicado: (2023)

Immunogenic cell death-associated biomarkers classification predicts prognosis and immunotherapy efficacy in pancreatic ductal adenocarcinoma
por: Peng, Wenguang, et al.
Publicado: (2023)

Investigation of M2 macrophage-related gene affecting patients prognosis and drug sensitivity in non-small cell lung cancer: Evidence from bioinformatic and experiments
por: Zeng, Zhen, et al.
Publicado: (2022)

The Ferroptosis-Related Noncoding RNA Signature as a Novel Prognostic Biomarker in the Tumor Microenvironment, Immunotherapy, and Drug Screening of Gastric Adenocarcinoma
por: Chen, Xinming, et al.
Publicado: (2021)

Identifying and Validating Potential Biomarkers of Early Stage Lung Adenocarcinoma Diagnosis and Prognosis
por: Chen, Yingji, et al.
Publicado: (2021)

Characterization of lipid droplet metabolism patterns identified prognosis and tumor microenvironment infiltration in gastric cancer
por: Liu, Mengxiao, et al.
Publicado: (2023)

Characterization of Tumor Microenvironment in Lung Adenocarcinoma Identifies Immune Signatures to Predict Clinical Outcomes and Therapeutic Responses
por: Chen, Donglai, et al.
Publicado: (2021)

Upregulated FADD is associated with poor prognosis, immune exhaustion, tumor malignancy, and immunotherapy resistance in patients with lung adenocarcinoma
por: He, Miao, et al.
Publicado: (2023)

Comprehensive Study of Tumor Immune Microenvironment and Relevant Genes in Hepatocellular Carcinoma Identifies Potential Prognostic Significance
por: Chen, Wenbiao, et al.
Publicado: (2020)

Immunometabolism in the tumor microenvironment and its related research progress
por: Zhang, Ziheng, et al.
Publicado: (2022)

The Tumor Microenvironment and Immunotherapy of Oropharyngeal Squamous Cell Carcinoma
por: Welters, Marij J. P., et al.
Publicado: (2020)

Pan-cancer analysis of trophinin-associated protein with potential implications in clinical significance, prognosis, and tumor microenvironment in human cancers
por: Li, Zhenfen, et al.
Publicado: (2022)

Neutrophil extracellular traps-associated modification patterns depict the tumor microenvironment, precision immunotherapy, and prognosis of clear cell renal cell carcinoma
por: Teng, Zhi-Hai, et al.
Publicado: (2022)

Construction of an interferon regulatory factors-related risk model for predicting prognosis, immune microenvironment and immunotherapy in clear cell renal cell carcinoma
por: Pan, Hao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8kjg3468uje48kqtlm6r3p5gsm