Reducing brain TACE activity improves neuroinflammation and cardiac function in heart failure rats

Tumor necrosis factor (TNF)-α converting enzyme (TACE) is a key metalloprotease mediating ectodomain shedding of a variety of inflammatory mediators, substrates, and growth factors. We previously reported that TACE-mediated production of TNF-α in the hypothalamic paraventricular nucleus (PVN) contri...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Xue, Baojian, Irfan, Nafis Md, Beltz, Terry, Weiss, Robert M, Johnson, Alan Kim, Felder, Robert B, Wei, Shun-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682140/
https://www.ncbi.nlm.nih.gov/pubmed/36439267
http://dx.doi.org/10.3389/fphys.2022.1052304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682140/
https://www.ncbi.nlm.nih.gov/pubmed/36439267
http://dx.doi.org/10.3389/fphys.2022.1052304

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