Nicotinamide riboside kinases regulate skeletal muscle fiber-type specification and are rate-limiting for metabolic adaptations during regeneration

Nicotinamide riboside kinases (NRKs) control the conversion of dietary Nicotinamide Riboside (NR) to NAD(+), but little is known about their contribution to endogenous NAD(+) turnover and muscle plasticity during skeletal muscle growth and remodeling. Using NRK1/2 double KO (NRKdKO) mice, we investi...

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Detalles Bibliográficos
Autores principales: Sonntag, Tanja, Ancel, Sara, Karaz, Sonia, Cichosz, Paulina, Jacot, Guillaume, Giner, Maria Pilar, Sanchez-Garcia, José Luis, Pannérec, Alice, Moco, Sofia, Sorrentino, Vincenzo, Cantó, Carles, Feige, Jérôme N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682158/
https://www.ncbi.nlm.nih.gov/pubmed/36438552
http://dx.doi.org/10.3389/fcell.2022.1049653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682158/
https://www.ncbi.nlm.nih.gov/pubmed/36438552
http://dx.doi.org/10.3389/fcell.2022.1049653

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