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The ventilatory depressant actions but not the antinociceptive effects of morphine are blunted in rats receiving intravenous infusion of L-cysteine ethyl ester

This study demonstrates that intravenous infusion of the cell-penetrant thiol ester, L-cysteine ethyl ester (L-CYSee), to adult male Sprague-Dawley rats elicited (a) minor alterations in frequency of breathing, expiratory time, tidal volume, minute ventilation, or expiratory drive but pronounced cha...

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Detalles Bibliográficos
Autores principales: Lewis, Tristan H.J., May, Walter J., Young, Alex P., Bates, James N., Baby, Santhosh M., Getsy, Paulina M., Ryan, Rita M., Hsieh, Yee-Hsee, Seckler, James M., Lewis, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682160/
https://www.ncbi.nlm.nih.gov/pubmed/36411626
http://dx.doi.org/10.1016/j.biopha.2022.113939