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Generation of high affinity ICAM-1-specific nanobodies and evaluation of their suitability for allergy treatment
The nasal cavity is an important site of allergen entry. Hence, it represents an organ where trans-epithelial allergen penetration and subsequent IgE-mediated allergic inflammation can potentially be inhibited. Intercellular adhesion molecule 1 (ICAM-1) is highly expressed on the surface of respirat...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682242/ https://www.ncbi.nlm.nih.gov/pubmed/36439110 http://dx.doi.org/10.3389/fimmu.2022.1022418 |