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Generation of high affinity ICAM-1-specific nanobodies and evaluation of their suitability for allergy treatment

The nasal cavity is an important site of allergen entry. Hence, it represents an organ where trans-epithelial allergen penetration and subsequent IgE-mediated allergic inflammation can potentially be inhibited. Intercellular adhesion molecule 1 (ICAM-1) is highly expressed on the surface of respirat...

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Detalles Bibliográficos
Autores principales:	Zettl, Ines, Ivanova, Tatiana, Zghaebi, Mohammed, Rutovskaya, Marina V., Ellinger, Isabella, Goryainova, Oksana, Kollárová, Jessica, Villazala-Merino, Sergio, Lupinek, Christian, Weichwald, Christina, Drescher, Anja, Eckl-Dorna, Julia, Tillib, Sergei V., Flicker, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682242/ https://www.ncbi.nlm.nih.gov/pubmed/36439110 http://dx.doi.org/10.3389/fimmu.2022.1022418

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