CD8(+) T cell/cancer-associated fibroblast ratio stratifies prognostic and predictive responses to immunotherapy across multiple cancer types

BACKGROUND: Cancer-associated fibroblasts (CAFs) within the tumor microenvironment (TME) are critical for immune suppression by restricting immune cell infiltration in the tumor stromal zones from penetrating tumor islands and changing their function status, particularly for CD8(+) T cells. However,...

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Detalles Bibliográficos
Autores principales: Zheng, Xinlong, Jiang, Kan, Xiao, Weijin, Zeng, Dongqiang, Peng, Wenying, Bai, Jing, Chen, Xiaohui, Li, Pansong, Zhang, Longfeng, Zheng, Xiaobin, Miao, Qian, Wang, Haibo, Wu, Shiwen, Xu, Yiquan, Xu, Haipeng, Li, Chao, Li, Lifeng, Gao, Xuan, Zheng, Suya, Li, Junhui, Wang, Deqiang, Zhou, Zhipeng, Xia, Xuefeng, Yang, Shanshan, Li, Yujing, Cui, Zhaolei, Zhang, Qiuyu, Chen, Ling, Lin, Xiandong, Lin, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682254/
https://www.ncbi.nlm.nih.gov/pubmed/36439099
http://dx.doi.org/10.3389/fimmu.2022.974265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682254/
https://www.ncbi.nlm.nih.gov/pubmed/36439099
http://dx.doi.org/10.3389/fimmu.2022.974265

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