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New validated spectrofluorimetric protocol for colistin assay through condensation with 2,2-dihydroxyindan-1,3-dione: application to content uniformity testing

A new, cost-effective and sensitive spectroscopic assay for the quantification of Colistin Sulfate (CS) and its prodrug colistimethate sodium (CMS) has been developed and validated. The validated technique depends on the condensation of the studied drug with 2,2-dihydroxyindan-1,3-dione (ninhydrin)...

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Detalles Bibliográficos
Autores principales: Attia, Tamer Z., Abdelmajed, Mahmoud A., Omar, Mahmoud A., Al Thagfan, Sultan S., Badr El-Din, Khalid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682325/
https://www.ncbi.nlm.nih.gov/pubmed/36505680
http://dx.doi.org/10.1039/d2ra04259b