High-MOI induces rapid CRISPR spacer acquisition in Sulfolobus from an acr deficient virus

Spacer acquisition, the first step in CRISPR-Cas adaptive immunity, plays a critical role in establishing and strengthening host defense against mobile genetic elements (MGEs). Here we present a host-virus system, where an increase in the multiplicity of infection (MOI), of a CRISPR-Cas susceptible...

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Detalles Bibliográficos
Autores principales: Bhoobalan-Chitty, Yuvaraj, Duan, Xiaoxiao, Peng, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682418/
https://www.ncbi.nlm.nih.gov/pubmed/36439395
http://dx.doi.org/10.17912/micropub.biology.000664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682418/
https://www.ncbi.nlm.nih.gov/pubmed/36439395
http://dx.doi.org/10.17912/micropub.biology.000664

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