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Association of Klotho Protein Levels and KL-VS Heterozygosity With Alzheimer Disease and Amyloid and Tau Burden

IMPORTANCE: Identification of proteins and genetic factors that reduce Alzheimer disease (AD) pathology is of importance when searching for novel AD treatments. Heterozygosity of the KL-VS haplotype has been associated with reduced amyloid and tau burden. Whether this association is mediated by the...

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Detalles Bibliográficos
Autores principales: Grøntvedt, Gøril Rolfseng, Sando, Sigrid Botne, Lauridsen, Camilla, Bråthen, Geir, White, Linda R., Salvesen, Øyvind, Aarsland, Dag, Hessen, Erik, Fladby, Tormod, Waterloo, Knut, Scheffler, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682425/
https://www.ncbi.nlm.nih.gov/pubmed/36413367
http://dx.doi.org/10.1001/jamanetworkopen.2022.43232