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The role of α-sheet structure in amyloidogenesis: characterization and implications

Amyloid diseases are linked to protein misfolding whereby the amyloidogenic protein undergoes a conformational change, aggregates and eventually forms amyloid fibrils. While the amyloid fibrils and plaques are hallmarks of these diseases, they typically form late in the disease process and do not co...

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Detalles Bibliográficos
Autores principales: Prosswimmer, Tatum, Daggett, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682440/
https://www.ncbi.nlm.nih.gov/pubmed/36416010
http://dx.doi.org/10.1098/rsob.220261