Testing of drugs using human feto-maternal interface organ-on-chips provide insights into pharmacokinetics and efficacy

Objectives: To improve preclinical drug testing during pregnancy, we developed multiple microfluidic organ-on-chip (OOC) devices that represent the structure, functions, and responses of the two feto-maternal interfaces (FMis) in humans (fetal membrane [FMi-OOC] and placenta [PLA-OOC]). This study u...

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Detalles Bibliográficos
Autores principales: Richardson, Lauren S., K. Kammala, Ananth, Costantine, Maged M., Fortunato, Stephen J., Radnaa, Enkhtuya, Kim, Sungjin, Taylor, Robert N., Han, Arum, Menon, Ramkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682442/
https://www.ncbi.nlm.nih.gov/pubmed/36322152
http://dx.doi.org/10.1039/d2lc00691j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682442/
https://www.ncbi.nlm.nih.gov/pubmed/36322152
http://dx.doi.org/10.1039/d2lc00691j

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