Cargando…
What Makes a Potent Nitrosamine? Statistical Validation of Expert-Derived Structure–Activity Relationships
[Image: see text] The discovery of carcinogenic nitrosamine impurities above the safe limits in pharmaceuticals has led to an urgent need to develop methods for extending structure–activity relationship (SAR) analyses from relatively limited datasets, while the level of confidence required in that S...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682520/ https://www.ncbi.nlm.nih.gov/pubmed/36302501 http://dx.doi.org/10.1021/acs.chemrestox.2c00199 |