Toward Realistic Dosimetry In Vitro: Determining Effective Concentrations of Test Substances in Cell Culture and Their Prediction by an In Silico Mass Balance Model

[Image: see text] Nominal concentrations (C(Nom)) in cell culture media are routinely used to define concentration–effect relationships in the in vitro toxicology. The actual concentration in the medium (C(Medium)) can be affected by adsorption processes, evaporation, or degradation of chemicals. Th...

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Detalles Bibliográficos
Autores principales: Dimitrijevic, Dunja, Fabian, Eric, Nicol, Beate, Funk-Weyer, Dorothee, Landsiedel, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682521/
https://www.ncbi.nlm.nih.gov/pubmed/36264934
http://dx.doi.org/10.1021/acs.chemrestox.2c00128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682521/
https://www.ncbi.nlm.nih.gov/pubmed/36264934
http://dx.doi.org/10.1021/acs.chemrestox.2c00128

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