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Toward Realistic Dosimetry In Vitro: Determining Effective Concentrations of Test Substances in Cell Culture and Their Prediction by an In Silico Mass Balance Model
[Image: see text] Nominal concentrations (C(Nom)) in cell culture media are routinely used to define concentration–effect relationships in the in vitro toxicology. The actual concentration in the medium (C(Medium)) can be affected by adsorption processes, evaporation, or degradation of chemicals. Th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682521/ https://www.ncbi.nlm.nih.gov/pubmed/36264934 http://dx.doi.org/10.1021/acs.chemrestox.2c00128 |