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Shared Clavulanate and Tazobactam Antigenic Determinants Activate T-Cells from Hypersensitive Patients

[Image: see text] β-Lactamase inhibitors such as clavulanic acid and tazobactam were developed to overcome β-lactam antibiotic resistance. Hypersensitivity reactions to these drugs have not been studied in detail, and the antigenic determinants that activate T-cells have not been defined. The object...

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Detalles Bibliográficos
Autores principales: Ariza, Adriana, Jaruthamsophon, Kanoot, Meng, Xiaoli, Labella, Marina, Adair, Kareena, Tailor, Arun, Sukasem, Chonlaphat, Whitaker, Paul, Peckham, Daniel, Pirmohamed, Munir, Torres, María José, Naisbitt, Dean John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682523/
https://www.ncbi.nlm.nih.gov/pubmed/36137197
http://dx.doi.org/10.1021/acs.chemrestox.2c00231