GALNT1 Enhances Malignant Phenotype of Gastric Cancer via Modulating CD44 Glycosylation to Activate the Wnt/β-catenin Signaling Pathway

O-glycosylation is a widespread post-translational modification of proteins. Aberrant O-glycosylation is a hallmark of cancer. Here, we show that the polypeptide N-acetylgalactosamine-transferase 1 (GALNT1) is frequently upregulated in gastric cancer and is correlated with poor survival. Overexpress...

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Detalles Bibliográficos
Autores principales: Zhang, Junchang, Wang, Han, Wu, Jing, Yuan, Cheng, Chen, Songyao, Liu, Shuhao, Huo, Mingyu, Zhang, Changhua, He, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682532/
https://www.ncbi.nlm.nih.gov/pubmed/36439876
http://dx.doi.org/10.7150/ijbs.73431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682532/
https://www.ncbi.nlm.nih.gov/pubmed/36439876
http://dx.doi.org/10.7150/ijbs.73431

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