4-Octyl itaconate regulates immune balance by activating Nrf2 and negatively regulating PD-L1 in a mouse model of sepsis

Introduction: Sepsis is a major global health challenge with high mortality rates and no effective treatment. Recent studies have suggested that sepsis may be associated with immune system dysfunction. Itaconate may exert anti-inflammatory effects via Nrf2 signaling. Although Nrf2 regulates oxidativ...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Wang, Yaxin, Yang, Wengchang, Yin, Yuping, Li, Chengguo, Ma, Xianxiong, Shi, Liang, Li, Ruidong, Tao, Kaixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682535/
https://www.ncbi.nlm.nih.gov/pubmed/36439878
http://dx.doi.org/10.7150/ijbs.74456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682535/
https://www.ncbi.nlm.nih.gov/pubmed/36439878
http://dx.doi.org/10.7150/ijbs.74456

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