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ELK1-mediated YTHDF1 drives prostate cancer progression by facilitating the translation of Polo-like kinase 1 in an m6A dependent manner

Background: N6-methyladenosine (m6A) is one of the most prevalent mRNA modifications in mammals, and it regulates the fate of modified RNA transcripts. In the current study, we aimed to elucidate the role of YTH m6A RNA-binding protein 1 (YTHDF1), a “reader” of m6A modification, in prostate cancer t...

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Detalles Bibliográficos
Autores principales: Li, Peizhang, Shi, Yuanping, Gao, Dajun, Xu, Huan, Zou, Yun, Wang, Zhong, Li, Wenzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682537/
https://www.ncbi.nlm.nih.gov/pubmed/36439881
http://dx.doi.org/10.7150/ijbs.75063