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Interpreting a Bayesian phase II futility clinical trial
BACKGROUND: A resurgence of research into phase II trial design in the mid-2000s led to the use of futility designs in a wide variety of disease areas. Phase II futility studies differ from efficacy studies in that their null hypothesis is that treatment, relative to control, does not meet or exceed...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682669/ https://www.ncbi.nlm.nih.gov/pubmed/36414953 http://dx.doi.org/10.1186/s13063-022-06877-7 |