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Temporal regulation of notch activation improves arteriovenous fistula maturation

BACKGROUND: Arteriovenous fistula (AVF) maturation is a process involving remodeling of venous arm of the AVFs. It is a challenge to balance adaptive AVF remodeling and neointima formation. In this study we temporally controlled Notch activation to promote AVF maturation while avoiding neointima for...

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Detalles Bibliográficos
Autores principales: Guo, Qunying, Chen, Guang, Cheng, Hunter, Qing, Ying, Truong, Luan, Ma, Quan, Wang, Yun, Cheng, Jizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682688/
https://www.ncbi.nlm.nih.gov/pubmed/36419038
http://dx.doi.org/10.1186/s12967-022-03727-7