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Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients

BACKGROUND: Sedative agents may variably impact the stress response. Dexmedetomidine is a sympatholytic alpha(2)-adrenergic agonist mainly used as a second-line sedative agent in mechanically ventilated patients. We hypothesised that early sedation with dexmedetomidine as the primary agent would res...

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Detalles Bibliográficos
Autores principales: Moore, John P. R., Shehabi, Yahya, Reade, Michael C., Bailey, Michael, Fraser, John F., Murray, Lauren, Anstey, Christopher, Singer, Mervyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682690/
https://www.ncbi.nlm.nih.gov/pubmed/36419197
http://dx.doi.org/10.1186/s13054-022-04237-0