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Synthesis, biological evaluation, and computational studies of some novel quinazoline derivatives as anticancer agents

A series of quinazolinone derivatives (7a–7h) were synthesized as antiproliferative agents. All compounds, were synthesized through three steps method and structurally evaluated by FTIR, (1)H-NMR, (13)CNMR and Mass spectroscopy. Their cytotoxic activities were assessed using MTT protocol against thr...

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Detalles Bibliográficos
Autores principales: Emami, Leila, Khabnadideh, Soghra, Faghih, Zahra, Farahvasi, Farnoosh, Zonobi, Fatemeh, Gheshlaghi, Saman Zare, Daili, Shadi, Ebrahimi, Ali, Faghih, Zeinab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682696/
https://www.ncbi.nlm.nih.gov/pubmed/36419100
http://dx.doi.org/10.1186/s13065-022-00893-z