CD6-mediated inhibition of T cell activation via modulation of Ras

BACKGROUND: CD6 is one of many cell surface receptors known to regulate signal transduction upon T cell activation. However, whether CD6 mediates costimulatory or inhibitory signals is controversial. When T cells engage with antigen presenting cells (APCs), CD6 interacts with its ligand CD166 at the...

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Detalles Bibliográficos
Autores principales: Henriques, Sónia N., Oliveira, Liliana, Santos, Rita F., Carmo, Alexandre M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682754/
https://www.ncbi.nlm.nih.gov/pubmed/36414966
http://dx.doi.org/10.1186/s12964-022-00998-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682754/
https://www.ncbi.nlm.nih.gov/pubmed/36414966
http://dx.doi.org/10.1186/s12964-022-00998-x

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