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Characterization of the effect of histone deacetylation inhibitors on CD8(+) T cells in the context of aging
BACKGROUND: Posttranslational protein modifications regulate essential cellular processes, including the immune cell activation. Despite known age-related alterations of the phenotype, composition and cytokine profiles of immune cells, the role of acetylation in the aging process of the immune syste...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682763/ https://www.ncbi.nlm.nih.gov/pubmed/36419167 http://dx.doi.org/10.1186/s12967-022-03733-9 |