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Characterization of the effect of histone deacetylation inhibitors on CD8(+) T cells in the context of aging

BACKGROUND: Posttranslational protein modifications regulate essential cellular processes, including the immune cell activation. Despite known age-related alterations of the phenotype, composition and cytokine profiles of immune cells, the role of acetylation in the aging process of the immune syste...

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Detalles Bibliográficos
Autores principales:	Toma, Georgiana, Karapetian, Eliza, Massa, Chiara, Quandt, Dagmar, Seliger, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682763/ https://www.ncbi.nlm.nih.gov/pubmed/36419167 http://dx.doi.org/10.1186/s12967-022-03733-9

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