Using information from network meta-analyses to optimize the power and sample allocation of a subsequent trial with a new treatment

BACKGROUND: A critical step in trial design is determining the sample size and sample allocation to ensure the proposed study has sufficient power to test the hypothesis of interest: superiority, equivalence, or non-inferiority. When data are available from prior trials and leveraged with the new tr...

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Detalles Bibliográficos
Autores principales: Hu, Dapeng, Wang, Chong, Ye, Fangshu, O’Connor, Annette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682784/
https://www.ncbi.nlm.nih.gov/pubmed/36418960
http://dx.doi.org/10.1186/s12874-022-01792-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682784/
https://www.ncbi.nlm.nih.gov/pubmed/36418960
http://dx.doi.org/10.1186/s12874-022-01792-6

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