CSP I-plus modified rEndostatin inhibits hepatocellular carcinoma metastasis via down-regulation of VEGFA and integrinβ1

BACKGROUND: In our previous study, N end of the Circumsporozoite protein (CSP I-plus) modified recombinant human Endostatin (rEndostatin, endostar) (rES-CSP) was constructed, which had antiangiogenic capability and bound to hepatocellular carcinoma in vivo and in vitro. In this study, the inhibition...

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Detalles Bibliográficos
Autores principales: Chen, Xueqin, Wang, Yan, Liu, Hancong, Zhang, Jingjing, Wang, Jie, Jin, Xiaobao, Ma, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682839/
https://www.ncbi.nlm.nih.gov/pubmed/36419008
http://dx.doi.org/10.1186/s12885-022-10318-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682839/
https://www.ncbi.nlm.nih.gov/pubmed/36419008
http://dx.doi.org/10.1186/s12885-022-10318-8

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