Discovery of pentaene polyols by the activation of an enediyne gene cluster: biosynthetic implications for 9-membered enediyne core structures

The identification and characterization of enediyne polyketide synthases (PKSEs) revealed that PKSE-bound polyene is a common intermediate, while its subsequent tailoring steps to enediyne cores remain obscure. Herein, we report pentaene polyols 5–7 and cinnamic acid derivatives 8 and 9 biosynthesiz...

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Detalles Bibliográficos
Autores principales: Pan, Jian, Tan, Qingwen, Zhu, Saibin, Yan, Xiaohui, Li, Yu, Zhuang, Zhoukang, Zhu, Xiangcheng, Duan, Yanwen, Huang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682884/
https://www.ncbi.nlm.nih.gov/pubmed/36507168
http://dx.doi.org/10.1039/d2sc04379c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682884/
https://www.ncbi.nlm.nih.gov/pubmed/36507168
http://dx.doi.org/10.1039/d2sc04379c

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