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Analysis of the Prevalence of Binding and Neutralizing Antibodies against 39 Human Adenovirus Types in Student Cohorts Reveals Low-Prevalence Types and a Decline in Binding Antibody Levels during the SARS-CoV-2 Pandemic

Human adenoviruses (HAdVs) are important tools for vector development for applications such as immunization, oncolytic therapy, or gene therapy. However, their potential is limited by preexisting immunity against HAdV; therefore, it is important for future vector design to identify HAdV types of low...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyan, Kerkmann, Leonie, Hetzel, Mario, Windmann, Sonja, Trilling, Mirko, Zhang, Wenli, Ehrhardt, Anja, Bayer, Wibke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9682995/
https://www.ncbi.nlm.nih.gov/pubmed/36342295
http://dx.doi.org/10.1128/jvi.01133-22