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The Origin of Internal Genes Contributes to the Replication and Transmission Fitness of H7N9 Avian Influenza Virus

H9N2 avian influenza viruses (AIVs) have donated internal gene segments during the emergence of zoonotic AIVs, including H7N9. We used reverse genetics to generate A/Anhui/1/13 (H7N9) and three reassortant viruses (2:6 H7N9) which contained the hemagglutinin and neuraminidase from Anhui/13 (H7N9) an...

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Detalles Bibliográficos
Autores principales: James, Joe, Bhat, Sushant, Walsh, Sarah K., Karunarathna, Thusitha K., Sadeyen, Jean-Remy, Chang, Pengxiang, Sealy, Joshua E., Mahmood, Sahar, Mollett, Benjamin C., Slomka, Marek J., Brookes, Sharon M., Iqbal, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683025/
https://www.ncbi.nlm.nih.gov/pubmed/36342296
http://dx.doi.org/10.1128/jvi.01290-22