Design, synthesis and biological evaluation of 4-aminoquinoline derivatives as receptor-interacting protein kinase 2 (RIPK2) inhibitors

Receptor-interacting protein kinase 2 (RIPK2) is an essential protein kinase mediating signal transduction by NOD1 and NOD2, which play an important role in regulating immune signalling. In this study, we designed and synthesised a novel series of 4-aminoquinoline-based derivatives as RIPK2 inhibito...

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Detalles Bibliográficos
Autores principales: Fan, Tiantian, Ji, Yinchun, Chen, Danqi, Peng, Xia, Ai, Jing, Xiong, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683047/
https://www.ncbi.nlm.nih.gov/pubmed/36408835
http://dx.doi.org/10.1080/14756366.2022.2148317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683047/
https://www.ncbi.nlm.nih.gov/pubmed/36408835
http://dx.doi.org/10.1080/14756366.2022.2148317

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