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Associations of GHR, IGF-1 and IGFBP-3 expression in adipose tissue cells with obesity-related alterations in corresponding circulating levels and adipose tissue function in children

Components of the growth hormone (GH) axis, such as insulin-like growth factor-1 (IGF-1), IGF-1 binding protein-3 (IGFBP-3), GH receptor (GHR) and GH-binding protein (GHBP), regulate growth and metabolic pathways. Here, we asked if serum levels of these factors are altered with overweight/obesity an...

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Detalles Bibliográficos
Autores principales: Kempf, Elena, Landgraf, Kathrin, Vogel, Tim, Spielau, Ulrike, Stein, Robert, Raschpichler, Matthias, Kratzsch, Jürgen, Kiess, Wieland, Stanik, Juraj, Körner, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683049/
https://www.ncbi.nlm.nih.gov/pubmed/36384443
http://dx.doi.org/10.1080/21623945.2022.2148886