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Immunological Control of HIV-1 Disease Progression by Rare Protective HLA Allele

Rare HLA alleles such as HLA-B57 are associated with slow progression to AIDS. However, the evidence for the advantage of rare protective alleles is limited, and the mechanism is still unclear. Although the prevalence of HLA-B*67:01 is only 1.2% in Japan, HLA-B*67:01-positive (HLA-B*67:01(+)) indivi...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Chikata, Takayuki, Kuse, Nozomi, Murakoshi, Hayato, Gatanaga, Hiroyuki, Oka, Shinichi, Takiguchi, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683060/
https://www.ncbi.nlm.nih.gov/pubmed/36326273
http://dx.doi.org/10.1128/jvi.01248-22