A screen of small molecule and genetic modulators of life span in female Drosophila identifies etomoxir, RH5849 and unanticipated temperature effects

Mifepristone increases life span in female Drosophila melanogaster, and its molecular target(s) remain unclear. Here small molecule and genetic interventions were tested for ability to mimic mifepristone, or to decrease life span in a way that can be rescued by mifepristone. Etomoxir inhibits lipid...

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Detalles Bibliográficos
Autores principales: N. Landis, Gary, Ko, Sebastian, Peng, Oscar, Bognar, Brett, Khmelkov, Michael, S. Bell, Hans, Tower, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683069/
https://www.ncbi.nlm.nih.gov/pubmed/36412257
http://dx.doi.org/10.1080/19336934.2022.2149209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683069/
https://www.ncbi.nlm.nih.gov/pubmed/36412257
http://dx.doi.org/10.1080/19336934.2022.2149209

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