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A screen of small molecule and genetic modulators of life span in female Drosophila identifies etomoxir, RH5849 and unanticipated temperature effects
Mifepristone increases life span in female Drosophila melanogaster, and its molecular target(s) remain unclear. Here small molecule and genetic interventions were tested for ability to mimic mifepristone, or to decrease life span in a way that can be rescued by mifepristone. Etomoxir inhibits lipid...
Autores principales: | N. Landis, Gary, Ko, Sebastian, Peng, Oscar, Bognar, Brett, Khmelkov, Michael, S. Bell, Hans, Tower, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683069/ https://www.ncbi.nlm.nih.gov/pubmed/36412257 http://dx.doi.org/10.1080/19336934.2022.2149209 |
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