CD147 Targeting by AC-73 Induces Autophagy and Reduces Intestinal Fibrosis Associated with TNBS Chronic Colitis

BACKGROUND AND AIMS: Intestinal fibrosis is a common complication of inflammatory bowel diseases. Medical treatment of intestinal fibrosis is an unmet therapeutic need. CD147 overexpression can induce myofibroblast differentiation associated with extracellular matrix deposition, favouring the develo...

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Detalles Bibliográficos
Autores principales: Butera, Alessia, Quaranta, Maria Teresa, Crippa, Luca, Spinello, Isabella, Saulle, Ernestina, Di Carlo, Nazzareno, Campanile, Doriana, Boirivant, Monica, Labbaye, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683082/
https://www.ncbi.nlm.nih.gov/pubmed/35833587
http://dx.doi.org/10.1093/ecco-jcc/jjac084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683082/
https://www.ncbi.nlm.nih.gov/pubmed/35833587
http://dx.doi.org/10.1093/ecco-jcc/jjac084

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