Cargando…

CD147 Targeting by AC-73 Induces Autophagy and Reduces Intestinal Fibrosis Associated with TNBS Chronic Colitis

BACKGROUND AND AIMS: Intestinal fibrosis is a common complication of inflammatory bowel diseases. Medical treatment of intestinal fibrosis is an unmet therapeutic need. CD147 overexpression can induce myofibroblast differentiation associated with extracellular matrix deposition, favouring the develo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Butera, Alessia, Quaranta, Maria Teresa, Crippa, Luca, Spinello, Isabella, Saulle, Ernestina, Di Carlo, Nazzareno, Campanile, Doriana, Boirivant, Monica, Labbaye, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683082/ https://www.ncbi.nlm.nih.gov/pubmed/35833587 http://dx.doi.org/10.1093/ecco-jcc/jjac084

Ejemplares similares

The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells
por: Spinello, Isabella, et al.
Publicado: (2019)

Advances in Understanding the Links between Metabolism and Autophagy in Acute Myeloid Leukemia: From Biology to Therapeutic Targeting
por: Saulle, Ernestina, et al.
Publicado: (2023)

Targeting Lactate Metabolism by Inhibiting MCT1 or MCT4 Impairs Leukemic Cell Proliferation, Induces Two Different Related Death-Pathways and Increases Chemotherapeutic Sensitivity of Acute Myeloid Leukemia Cells
por: Saulle, Ernestina, et al.
Publicado: (2021)

CD3+CD4+LAP+Foxp3-Regulatory Cells of the Colonic Lamina Propria Limit Disease Extension in Ulcerative Colitis
por: Butera, Alessia, et al.
Publicado: (2018)

Resveratrol Pretreatment Ameliorates TNBS Colitis in Rats
por: Yildiz, Gulserap, et al.
Publicado: (2015)

The TNBS-induced colitis animal model: An overview
por: Antoniou, Efstathios, et al.
Publicado: (2016)

Kalopanaxsaponin B Ameliorates TNBS-Induced Colitis in Mice
por: Jeong, Jun-ju, et al.
Publicado: (2012)

Hemin reduces inflammation associated with TNBS-induced colitis
por: Mateus, Vanessa, et al.
Publicado: (2018)

Effects of Rhizophora mangle on Experimental Colitis Induced by TNBS in Rats
por: de Faria, Felipe Meira, et al.
Publicado: (2012)

Royal Jelly and Its Dual Role in TNBS Colitis in Mice
por: Manzo, Luis Paulo, et al.
Publicado: (2015)

Anti-inflammatory Effects of Flavonoids on TNBS-induced Colitis of Rats
por: Joo, Minjae, et al.
Publicado: (2015)

Altered sympathovagal balance and pain hypersensitivity in TNBS-induced colitis
por: Ciesielczyk, Katarzyna, et al.
Publicado: (2016)

Identification of β-Dystrobrevin as a Direct Target of miR-143: Involvement in Early Stages of Neural Differentiation
por: Quaranta, Maria Teresa, et al.
Publicado: (2016)

Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic Cells
por: Paolillo, Rosa, et al.
Publicado: (2015)

BTZO-15, an ARE-Activator, Ameliorates DSS- and TNBS-Induced Colitis in Rats
por: Yukitake, Hiroshi, et al.
Publicado: (2011)

The JNK Inhibitor XG-102 Protects against TNBS-Induced Colitis
por: Reinecke, Kirstin, et al.
Publicado: (2012)

Effect of Glucans from Caripia montagnei Mushroom on TNBS-Induced Colitis
por: da Nascimento Santos, Marilia S., et al.
Publicado: (2014)

Preventive effects of bovine colostrum supplementation in TNBS-induced colitis in mice
por: Filipescu, Iulia Elena, et al.
Publicado: (2018)

Changes in enteroendocrine and immune cells following colitis induction by TNBS in rats
por: El-Salhy, Magdy, et al.
Publicado: (2016)

Prenylated flavonoid morusin protects against TNBS-induced colitis in rats
por: Vochyánová, Zora, et al.
Publicado: (2017)

Effect of TNBS-induced colitis on enteric neuronal subpopulations in adult zebrafish
por: Uyttebroek, Leen, et al.
Publicado: (2020)

Mechanism by which oleracein E alleviates TNBS-induced ulcerative colitis
por: Huang, Yun, et al.
Publicado: (2023)

Effect of Carbamylated Erythropoietin in a Chronic Model of TNBS-Induced Colitis
por: Silva, Inês, et al.
Publicado: (2023)

Autocrine Role of Angiopoietins during Megakaryocytic Differentiation
por: Saulle, Ernestina, et al.
Publicado: (2012)

Crocetin Reduces TNBS-Induced Experimental Colitis in Mice by Downregulation of NFkB
por: Kazi, Hamid A., et al.
Publicado: (2009)

Glutamine Treatment Attenuates Endoplasmic Reticulum Stress and Apoptosis in TNBS-Induced Colitis
por: Crespo, Irene, et al.
Publicado: (2012)

Hyperbaric oxygen therapy ameliorates TNBS-induced acute distal colitis in rats
por: Parra, Rogério S, et al.
Publicado: (2015)

Local Treatment with Lactate Prevents Intestinal Inflammation in the TNBS-Induced Colitis Model
por: Iraporda, Carolina, et al.
Publicado: (2016)

Enteroendocrine cells, stem cells and differentiation progenitors in rats with TNBS-induced colitis
por: El-Salhy, Magdy, et al.
Publicado: (2016)

Oral Tolerance Induced by OVA Intake Ameliorates TNBS-Induced Colitis in Mice
por: Paiatto, Lisiery N., et al.
Publicado: (2017)

Anti-inflammatory effect of Chang-An-Shuan on TNBS-induced experimental colitis in rats
por: Mi, Hong, et al.
Publicado: (2017)

Unconjugated bilirubin ameliorates the inflammation and digestive protease increase in TNBS-induced colitis
por: Zhou, Jin-An, et al.
Publicado: (2017)

Protective Effect of Dizocilpine (MK-801) On TNBS-Induced Experimental Colitis in Mice
por: Motaghi, Ehsan, et al.
Publicado: (2019)

The Prophylactic Use of Bovine Colostrum in a Murine Model of TNBS-Induced Colitis
por: Menchetti, Laura, et al.
Publicado: (2020)

Short chain fatty acids (SCFAs) improves TNBS-induced colitis in zebrafish
por: Morales Fénero, Camila, et al.
Publicado: (2021)

Chronic Experimental Model of TNBS-Induced Colitis to Study Inflammatory Bowel Disease
por: Silva, Inês, et al.
Publicado: (2022)

Anti-Inflammatory Effect of Topiramate in a Chronic Model of TNBS-Induced Colitis
por: Silva, Inês, et al.
Publicado: (2022)

The Mutyh Base Excision Repair Gene Influences the Inflammatory Response in a Mouse Model of Ulcerative Colitis
por: Casorelli, Ida, et al.
Publicado: (2010)

Effects of a Combination of Thyme and Oregano Essential Oils on TNBS-Induced Colitis in Mice
por: Bukovská, Alexandra, et al.
Publicado: (2007)

Effects of extract and essential oil of Rosmarinus officinalis L. on TNBS-induced colitis in rats
por: Minaiyan, M., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_sbimmvk98m9agv4slbfg1sekv6