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Distinct brain pathologies associated with Alzheimer’s disease biomarker-related phospho-tau 181 and phospho-tau 217 in App knock-in mouse models of amyloid-β amyloidosis

Phospho-tau 217, phospho-tau 231 and phospho-tau 181 in cerebrospinal fluid and plasma are promising biomarkers for the diagnosis of Alzheimer’s disease. All these p-tau proteins are detected in neurofibrillary tangles in brains obtained post-mortem from Alzheimer’s disease patients. However, increa...

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Detalles Bibliográficos
Autores principales: Hirota, Yu, Sakakibara, Yasufumi, Ibaraki, Kyoko, Takei, Kimi, Iijima, Koichi M, Sekiya, Michiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683396/
https://www.ncbi.nlm.nih.gov/pubmed/36440096
http://dx.doi.org/10.1093/braincomms/fcac286