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Distinct brain pathologies associated with Alzheimer’s disease biomarker-related phospho-tau 181 and phospho-tau 217 in App knock-in mouse models of amyloid-β amyloidosis
Phospho-tau 217, phospho-tau 231 and phospho-tau 181 in cerebrospinal fluid and plasma are promising biomarkers for the diagnosis of Alzheimer’s disease. All these p-tau proteins are detected in neurofibrillary tangles in brains obtained post-mortem from Alzheimer’s disease patients. However, increa...
Autores principales: | Hirota, Yu, Sakakibara, Yasufumi, Ibaraki, Kyoko, Takei, Kimi, Iijima, Koichi M, Sekiya, Michiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683396/ https://www.ncbi.nlm.nih.gov/pubmed/36440096 http://dx.doi.org/10.1093/braincomms/fcac286 |
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