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Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro

Preeclampsia is a multi-system disease that can have severe, even fatal implications for the mother and fetus. Abnormal placentation can lead to ischaemic tissue injury and placental inflammation. In turn, the placenta releases anti-angiogenic factors into the maternal circulation. These systemicall...

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Detalles Bibliográficos
Autores principales: Kadife, Elif, Hannan, Natalie, Harper, Alesia, Binder, Natalie, Beard, Sally, Brownfoot, Fiona C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683551/
https://www.ncbi.nlm.nih.gov/pubmed/36417467
http://dx.doi.org/10.1371/journal.pone.0271560