Host transcriptomic profiling of CD-1 outbred mice with severe clinical outcomes following infection with Orientia tsutsugamushi

Orientia tsutsugamushi is an obligately intracellular bacterium with endothelial tropism and can cause mild to lethal scrub typhus in humans. No vaccine is available for this reemerging and severely neglected infection. Previous scrub typhus studies have utilized inbred mice, yet such models have in...

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Detalles Bibliográficos
Autores principales: Thiriot, Joseph, Liang, Yuejin, Fisher, James, Walker, David H., Soong, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683618/
https://www.ncbi.nlm.nih.gov/pubmed/36417363
http://dx.doi.org/10.1371/journal.pntd.0010459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683618/
https://www.ncbi.nlm.nih.gov/pubmed/36417363
http://dx.doi.org/10.1371/journal.pntd.0010459

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