Reprogramming Müller glia to regenerate ganglion-like cells in adult mouse retina with developmental transcription factors
Many neurodegenerative diseases cause degeneration of specific types of neurons. For example, glaucoma leads to death of retinal ganglion cells, leaving other neurons intact. Neurons are not regenerated in the adult mammalian central nervous system. However, in nonmammalian vertebrates, glial cells...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683702/ https://www.ncbi.nlm.nih.gov/pubmed/36417510 http://dx.doi.org/10.1126/sciadv.abq7219 |